Why catalase in liver

Similarly, enzymes in the liver are also used to functioning at body temperature 37 degrees Celsius , so microwaving the blended liver to a temperature hotter than that should have damaged the catalase enzyme and clearly decreased the amount of bubbles when it was exposed to hydrogen peroxide. Cleanup Safely dispose of any raw liver meat used in this activity by putting it in the trash when you are done. Completely disinfect any surfaces that the raw liver meat touched during this activity, and be sure to thoroughly wash your hands with soap and warm water.

Already a subscriber? Sign in. Thanks for reading Scientific American. Create your free account or Sign in to continue. See Subscription Options. Go Paperless with Digital. Key concepts Chemistry Acids Bases Temperature Physiology Molecular biology Introduction Your liver is important for cleaning up any potentially dangerous substances you consume. Observations and results When exposed to hydrogen peroxide, did the blended liver bubble less when mixed with either the vinegar or baking soda compared with when it was untreated?

Build a Cooler. Get smart. Sign up for our email newsletter. Sign Up. Support science journalism. Knowledge awaits. See Subscription Options Already a subscriber? Catalase is an enzyme that occurs in almost all aerobic organisms. Its main metabolic function is to prevent oxidative damage to tissues induced by hydrogen peroxide which is a strong oxidizing agent.

Catalase is very effective in performing this task, since it has the highest turnover rate among all the enzymes. However, when the H 2 O 2 concentration increases because of decreased expression or activity of catalase, it migrates to cytosol and other organelles, causing cell injury and participating in the Fenton reaction, resulting in serious oxidative stress. To date, numerous studies have been shown to inhibit the pathogenesis of NAFLD, but treatment for this disease mainly depends on weight loss and exercise.

Revised 02 Mar Accepted 28 Mar Published 24 Apr Introduction Liver cancer is considered one of the most aggressive ones and corresponds to the third leading cause of cancer deaths worldwide [ 1 — 3 ]. Materials and Methods To evaluate the coffee protective effect on catalase system, we performed an in vivo experiment aiming to obtain preneoplastic induced rat livers. Table 1. Table 2. Catalase activity in the liver tissues , with standard deviations.

Figure 1. Letters A, B, and C correspond to three random livers from each group. Table 3. Figure 2. Darvesha, B. Aggarwal, and A. Manach, J. Hubert, R. Llorach, and A. Ferrari and E. Muriel and J. Monteiro and L. Lang, E. Yagar, R. Eggers, and T. Carvalho, M. Brigagao, M. Santos, F. Paula, A. Giusti-Paiva, and L. View at: Google Scholar C. Azevedo, J. Takarada, N. Costa, and D. Preedy, Ed. View at: Google Scholar H.

Eugster, M. Probst, F. Wurgler, and C. View at: Google Scholar W. Tassaneeyakul, Z. Mohamed, D. Birkett et al. Gressner, R. Weiskirchen, K. Breitkopf, and S. View at: Google Scholar P. Sahu, Ed. Vitaglione, F. Morisco, G. Mazzone et al. Wang and C. Thibault and J. Jones, K.